Генетика. Часть 7. Генетические основы иммунитета. Крюков В.И. - 90 стр.

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. .  7. . .
: , 2006. – 142 .
90
-
:


 (+)
 (
–
)
a
b
 (
–
)
c
d
. =
a
·
d
/
b
·
c
, -
 HLA-B8  [9 , .66].


HLA
-
B8
 (+)
 (
–
)
17
12
 (
–
)
189
811
. = 17
·
811
/
12
·
189 = 6
,1
    ,   
      . 
   ,    .

      .
, -
, .
. 4,  
HLA -
, .
 -
 ()  HLA B27. -
  –    -
 ,      (-
) .  HLA B27 
   .  B27  93%
, 
 8% . 
                                                        90


                                                                                                           -
          :

                                                               (+)                     (–)
                                   (+)                       a                     b
                                  (–)                        c                     d
                                                      . = a·d / b·c

                                                                                                    ,          -
                                              HLA-B8                                         [9 , .66].

                                                                 HLA-B8
                                                             (+)          (–)
                                   (+)                       17            12
                                  (–)                       189           811
                                                . = 17·811 / 12·189 = 6,1
                                                                                   ,
                                                                                                     .
                                                                ,                                              .

                                                                                                               .
                      ,                                                                                        -
  ,                                                                            .
                                             . 4,
HLA                                                                                                            -
                          ,                                                                               .
                                                                                                               -
                                         (                     )                        HLA B27.               -
                                               –                                                               -
                                    ,                                                         (                -
              )                                          .                              HLA B27
                                                          .               B27                             93%
                                                                ,
                                                        8%            .




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                  .           .          7.                                .                                   .
      :                           , 2006. – 142 .

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